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HIGH-PROFILE COMPUTER BREACHES DRAW ATTENTION TO SECURITY

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Posted on May 3, 2006

      In December, when an intruder breached the security of two Iowa State University computers containing encrypted credit card numbers of athletics department donors and Social Security numbers of more than 3,000 university employees, it prompted a swift investigation and immediate notification of those whose personal data may have been obtained, and caused many worries along the way.

      An investigation determined that the intruder hacked into the computers not to steal personal information but to store and distribute pirated movies or music. Nevertheless, the incident prompted efforts over the past four months to tighten security around sensitive information and a greater awareness among students, faculty and non-information technology staff that the threat of an attack exists and it is up to the entire university community to prevent another incident.

      "Until something happens, people don't always believe that it can happen," said Maury Hope, associate chief information officer in Information Technology Services at Iowa State.

      Incidents such as the one at Iowa State have created greater awareness nationwide of the widespread threat of computer security breaches. According to a recent FBI survey of more than 2,000 businesses in Iowa, Nebraska, New York and Texas, nearly nine out of 10 suffered from a computer virus, spyware or other online attack in 2004 or 2005. Though most companies use security software, computer hacking techniques are also far ahead of what they were 18 months ago, according to Loras Even, managing director of RSM McGladrey Inc.'s Integrated Technology Solutions.

      "If you block them, they're going to try to find a way to bypass it," he said.

      Federal legislation such as the Gramm-Leach-Bliley and Sarbanes-Oxley acts, as well as mandatory reporting legislation in several states, has brought more attention to the issues surrounding security and provided those in the security industry with more leverage in approaching and addressing these issues in the corporate sector, according to Kip Peters, enterprise information protection vice president for FBL Financial Group Inc. He now considers computer security an essential part of doing business.

      "It's raised the level of consciousness in the everyday person, and hopefully they're starting to ask questions when these things happen," he said.

      A computer security breach presents any organization with serious consequences, Even said. Customers and other outsiders may begin to question how safe and secure the organization and its information-protection systems may be. Businesses often face significant expenses in correcting the damage. According to the FBI study, the reported attacks inflicted an average of $24,000 in damages. Businesses may also face regulatory issues in correcting the problem.

      Many companies have addressed computer security by taking an "outside-in" approach Ð first building up a secure perimeter before turning to insider security threats, which accounted for 44 percent of the attacks documented in the FBI study. But changes in the corporate culture, such as an increase in telecommuters, make it nearly impossible to function with a heavily armored perimeter.

      "The perimeter is less defined, so now we're starting to look at what's going on inside (the company) a little different than in the past," Peters said. The best response, he said, is to use multiple layers of security to protect those lines of communications as much as possible without impairing communication.

      Even stresses the importance of educating people at all levels of an organization about computer security threats, and advises employees at all levels to be alert to suspicious e-mails or phone calls. All organizations should have some sort of incident response procedures, he added

      "As much as you train people and as many technology-based security measures you have in place, eventually an incident of some sort is going to occur, and it's better to have a planned response," Even said.

      But Hope and Peters say one of the greatest threats to corporate computer security today is the home computer. Most individuals today have broadband Internet access, which leaves home computers far more vulnerable to hackers. It becomes particularly worrisome for security specialists when people take their work home for the night or weekend, either on a laptop, disk or CD or by sending it via e-mail, sometimes leaving protected information, such as private client data, vulnerable to hackers.

      "You put that on a home computer and that, to me, is one of the things I really worry about because we have no control over it," Peters said.




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The subject is further treated with the pharmaceutically active agent, which is a drug selected from the group consisting of: a selective serotonin reuptake inhibitor; norepinephrine a tricyclic antidepressant; serotonin and noradrenaline reuptake inhibitor; a serotonin and dopamine reuptake inhibitor; a norepinephrine and dopamine reuptake inhibitor; a phenelzine-derivative selective serotonin reuptake inhibitor. A particular feature of the present invention is that treatment may be provided to a subject after has been treated with and tolerated a composition of the invention. In one embodiment, the subject, preferably a patient, is given pharmaceutical composition of the present invention. In another embodiment, the subject is given a combination of the pharmaceutical compositions invention. In yet another embodiment, the subject is given a combination of the pharmaceutical compositions invention and a agent. 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The method includes administering a therapeutically effective amount of pharmaceutical composition the present invention. patient is further treated with the therapeutically effective amount of pharmaceutical composition, which is a drug selected from the group consisting of: a selective serotonin reuptake inhibitor; norepinephrine a tricyclic antidepressant; serotonin and noradrenaline reuptake inhibitor; a serotonin and dopamine reuptake inhibitor; a norepinephrine and dopamine reuptake inhibitor; a phenelzine-derivative selective serotonin reuptake inhibitor. A particular feature of the present invention is that treatment may be provided to a patient after has been treated with a pharmaceutical composition of the invention. In another embodiment, subject, preferably a patient, is given pharmaceutical composition of the present invention. In yet another embodiment, the subject is given a combination of the pharmaceutical compositions invention and a agent. In one embodiment, the patient is given at least 2 pharmaceutical compositions of the present invention and at least one pharmaceutical agent. In another embodiment, the patient is given at least 4 pharmaceutical compositions of the present invention and at least one pharmaceutical agent. In another embodiment, the pharmaceutical compositions of present invention comprise at least 1 of: a serotonin norepinephrine reuptake inhibitor; and noradrenaline a serotonin Casodex 50mg $217.2 - $7.24 Per pill dopamine reuptake inhibitor; norepinephrine and a phenelzine-derivative selective serotonin reuptake inhibitor. The present invention contemplates a method of treating an indication depression is provided. The method includes administering a pharmaceutically effective amount of pharmaceutical composition the present invention. patient is further treated with the pharmaceutical composition, which is a drug selected from the group consisting of.

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Casodex 150 mg pret reatment). A second set of patients were excluded from analysis as the number of responders was not significantly changed in any group, suggesting the presence of a common dose-response for the various subgroups ( ). The final study group included 24 subjects with relapsing-remitting MS (mean age 47.4 ± 6.9 years, range 22-77 years; 13 women). They received 500 mg BID (n = 19) or placebo 17) once a day as usual. Three-month-follow-up results included the following results: mean PSS score, 7.6 ± 0.7 (range, 1-21) in the BID group and 8.9 ± 1.4 (range, 5-19) in the placebo group (adjusted change from baseline, −3.5 ± 0.7; 95% CI, −11.3 to 1.9; p = 0.03). One additional subject stopped BID after the first month due to safety concerns. At the 1-, 6-, and 12-month follow-up visits, the PSS scores were higher in both the BID and placebo groups (2.6 ± 0.9, 2.2 0.7 and 1.7 ± 0.6), respectively; however, the PSS scores were statistically significantly lower in the BID group than those in the placebo group at final follow-up visit (6.9 ± 0.5; 95% CI, −1.0 to 14.8; p = 0.02; see also Supplemental Table 4 online: http://links.lww.com/ACM/C14/B23 ). Discussion Here we found that the BIND-101, a proprietary formulation of interferon beta-1a (IFN-beta-1a) produced the largest increases in proportion of responders our study comparing a single dose to three or six doses daily for a total of 8-12 weeks. This study demonstrated that the increased efficacy of IFN-beta-1a for treatment with interferon beta-1a can be sustained for at least 2 canada drugs pharmacy winnipeg years among patients with relapsing-remitting MS. BIND-101 also extended the mean time to relapse and the duration of relapsing-remitting MS by approximately 18 months without a significant change in the incidence of side effects. To the best of our knowledge, this is the first randomized, controlled trial to investigate the effectiveness of BIND-101 in patients with relapsing-remitting MS. The results of BIND-101 demonstrated that the maximum benefit of BIND-101 was achieved among subjects who received higher doses compared with those who received a lower dose during the study. These results, based on our previous study showing that a daily dose of 400 what is the cost of casodex mg would lead to a median difference in responders between placebo and 100-mg BID [9], suggests that the higher dose may have produced more responders who were also able cost of casodex to tolerate the higher dose. Indeed, a similar increase in responsiveness was observed among persons with an HbA1c level <8.0% at the 12-month follow-up compared to a similar response among those with an HbA1c level of between 8.0% and 9.9%, as seen in BIND-101-treated subjects with an HbA1c of 16.4%. It is worth emphasizing that our patients were predominantly male with the highest number of relapses at 1 year and with the longest duration between periods of disability and progression. Indeed, a higher number of relapses is a clinical characteristic of relapsing-remitting MS [2,9,26,27]. The increased risk of relapse and the longer duration of symptoms might be explained by lower quality of life in subjects with MS. One study has observed that there are a higher proportion of patients with MS who had an average of 4 episodes per year (2.9) as compared with 5 (1.3) [28]. However, the study population was young (<50 years) and a higher proportion of males (<50%) was observed compared with females (<40%). In light of these findings, a greater risk of relapses and/or longer duration disability might be attributable to lower quality of life in MS patients than other casodex average cost chronic conditions, especially with regard to relapses [2]. We found that BIND-101 treatment led to improved quality of life (i.e., depressive and somatic symptoms as well quality of life overall). In addition, BIND-101 treatment may have prolonged the duration of time when patients were able to Betamethasone 0.05 prix continue their therapy, in some instances allowing for longer-term use and maintenance therapy [10,27]. Among our study subjects with RRMS, there was less response to BIND-101 on a global score compared with placebo. However, the differences in global scores are small (3.1 ± 2.2 v. 3.

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