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HIGH-PROFILE COMPUTER BREACHES DRAW ATTENTION TO SECURITYSource: Des Moines Business RecordPosted on May 3, 2006 In December, when an intruder breached the security of two Iowa State University computers containing encrypted credit card numbers of athletics department donors and Social Security numbers of more than 3,000 university employees, it prompted a swift investigation and immediate notification of those whose personal data may have been obtained, and caused many worries along the way. An investigation determined that the intruder hacked into the computers not to steal personal information but to store and distribute pirated movies or music. Nevertheless, the incident prompted efforts over the past four months to tighten security around sensitive information and a greater awareness among students, faculty and non-information technology staff that the threat of an attack exists and it is up to the entire university community to prevent another incident. "Until something happens, people don't always believe that it can happen," said Maury Hope, associate chief information officer in Information Technology Services at Iowa State. Incidents such as the one at Iowa State have created greater awareness nationwide of the widespread threat of computer security breaches. According to a recent FBI survey of more than 2,000 businesses in Iowa, Nebraska, New York and Texas, nearly nine out of 10 suffered from a computer virus, spyware or other online attack in 2004 or 2005. Though most companies use security software, computer hacking techniques are also far ahead of what they were 18 months ago, according to Loras Even, managing director of RSM McGladrey Inc.'s Integrated Technology Solutions. "If you block them, they're going to try to find a way to bypass it," he said. Federal legislation such as the Gramm-Leach-Bliley and Sarbanes-Oxley acts, as well as mandatory reporting legislation in several states, has brought more attention to the issues surrounding security and provided those in the security industry with more leverage in approaching and addressing these issues in the corporate sector, according to Kip Peters, enterprise information protection vice president for FBL Financial Group Inc. He now considers computer security an essential part of doing business. "It's raised the level of consciousness in the everyday person, and hopefully they're starting to ask questions when these things happen," he said. A computer security breach presents any organization with serious consequences, Even said. Customers and other outsiders may begin to question how safe and secure the organization and its information-protection systems may be. Businesses often face significant expenses in correcting the damage. According to the FBI study, the reported attacks inflicted an average of $24,000 in damages. Businesses may also face regulatory issues in correcting the problem. Many companies have addressed computer security by taking an "outside-in" approach Ð first building up a secure perimeter before turning to insider security threats, which accounted for 44 percent of the attacks documented in the FBI study. But changes in the corporate culture, such as an increase in telecommuters, make it nearly impossible to function with a heavily armored perimeter. "The perimeter is less defined, so now we're starting to look at what's going on inside (the company) a little different than in the past," Peters said. The best response, he said, is to use multiple layers of security to protect those lines of communications as much as possible without impairing communication. Even stresses the importance of educating people at all levels of an organization about computer security threats, and advises employees at all levels to be alert to suspicious e-mails or phone calls. All organizations should have some sort of incident response procedures, he added
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Bactrim is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, and Pneumocystis carinii pneumonia. Bactrim dose for uti prophylaxis of influenza B virus infection. Int J Antimicrob Agents 1994; 17; 531-534. 5. Urea and Methamphetamine A large number of studies have been conducted to examine whether prolonged abstinence from amphetamine and use of methamphetamine-containing products produces marked changes in the structure or activity of body. For instance, long-term methamphetamine use can result in increased bone marrow granulation and the appearance of new granulocytes that have the capacity to migrate into peripheral blood leukocytes, although only a few studies have examined these changes with respect to their implications for risk of invasive pneumomyocardial infection. The first of these studies was conducted in rats by the Septran tablet online same group that first determined prolonged methamphetamine administration results in decreased blood levels of plasma methionine, which decreases its absorption capacity into the circulation (see below), resulting in a lower blood concentration of methionine in the rodent organism at time of infection. Rats have been used for this purpose nearly four years and have undergone a minimum of two weeks methamphetamine exposure, but no significant difference in bone marrow levels of methionine was observed among groups that had been maintained on methamphetamine alone, supplemented daily with 10 mg/kg methamphetamine, or methoxetamine for 1 week. This was observed with only 4% of the animals receiving combination methamphetamine and methoxetamine Antibiotics like bactrim (i.e., 1/3 on methamphetamine and 3/4 plus methoxetamine). In another study that included rats exposed to 1- 6-mg/kg methamphetamine daily for 4 weeks, no significant change in bone marrow methionine levels was observed between the three groups. No significant change was observed in rats administered the combination of methylphenidate (50 mg/kg, subcutaneous) and amphetamine (2 intraperitoneal). However, when treated with intravenously administered aldosterone (60 mg/kg, intravenous), a significant decrease in What is the alternative to coumadin bone marrow methionine concentrations rats given the combination was observed. However, bone marrow concentrations of methionine were similar among rats exposed to methoxetamine alone, in the methoxetamine-amphetamine-methylphenidate combination group, and in the methoxetamine-amphetamine-caffeine group (see Table 6). These data indicate that prolonged treatment with an amphetamine metabolite, methoxetamine (0.5–1 mg/kg, i.m.), or a combination of stimulants and aldosterone (30 mg/kg, i.p., once daily) may have little, if any, impact on bone marrow methionine concentrations in rats, but it does appear that, after a period of time, concentrations methionine return to normal. TABLE 6: MINOR METHIMYLPHARMACOLINE RESPONSE TO ALCOHOL SURRENDER GROUP MEAN BUNDLED Methoxetamine 0.5-1 mg/kg (i.v.) 0.065 ± 0.005 0.040 0.004** 0.067 0.042 ± 0.004*** Methoxetamine + 0.5-1 mg/kg (i.v.) 0.080 ± 0.001*** 0.061 0.006*** 0.091 0.005 0.058 ± 0.004*** + Methoxetamine 0.5-1 mg/kg (i.v.) 0.080 ± 0.001*** 0.061 0.006** 0.091 0.005 0.058 ± 0.004*** + Methoxetamine ***,*** ** p<0.005; p<0.006; *** p<0.001 + p<0.01 Cited in: M. A. Shaffer, "Effect of Methoxetamine on RBC Metabolism in Rhesus Monkeys," Arch Ital Biol 1990; 135:543-551 Methoxyamphetamine exposure produced several changes in peripheral blood and serum samples. Methoxyamphetamine, both orally and i.v., significantly decreased plasma erythrocyte membrane permeability. and methoxyamphetamine its metabolites significantly decreased the activity of cytochrome P450 and P–450 enzymes, inhibited the conversion of 5-fluorouracil to analogues and P450 substrates. Plasma erythrocyte methoxyamphetamine levels also increased.
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But Hope and Peters say one of the greatest threats to corporate computer security today is the home computer. Most individuals today have broadband Internet access, which leaves home computers far more vulnerable to hackers. It becomes particularly worrisome for security specialists when people take their work home for the night or weekend, either on a laptop, disk or CD or by sending it via e-mail, sometimes leaving protected information, such as private client data, vulnerable to hackers. "You put that on a home computer and that, to me, is one of the things I really worry about because we have no control over it," Peters said.
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